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Co-Founder & Head of Technology at Gaius Therapeutics; computational biologist and ML researcher (PhD, UC San Diego); former professional basketball player.
Contact Information
| Name | Adam Klie |
| Professional Title | Co-Founder & Head of Technology, Gaius Therapeutics |
| adam@gaius.bio | |
| Location | San Diego, California |
| Website | https://adamklie.github.io |
Professional Summary
Co-Founder and Head of Technology at Gaius Therapeutics, an early-stage biotechnology company. Computational biologist and machine learning researcher (PhD, UC San Diego) working to decode the non-coding genome and translate it into new medicines. Former professional basketball player. The best way to reach me is by email — adam@gaius.bio or adamklie13@gmail.com.
Experience
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2026 - Present San Diego, CA
Co-Founder & Head of Technology
Gaius Therapeutics
An early-stage biotechnology company.
- Co-founded the company and lead its technology and computational platform.
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2025 - 2026 La Jolla, CA
Schmidt AI Postdoctoral Fellow
UC San Diego
Developed machine learning methods to link non-coding genetic variation to gene-regulatory function and built scalable tools for large-scale genomics.
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2019 - 2025 La Jolla, CA
Graduate Researcher (PhD)
UC San Diego — Carter Lab
PhD research on deep learning for regulatory genomics, advised by Hannah Carter.
- Created EUGENe, an open-source Python toolkit for deep learning in regulatory genomics (Nature Computational Science, 2023).
- Built sequence-to-function models to predict regulatory element activity and interpret non-coding variation.
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2023 - 2023 Palo Alto, CA
Visiting Researcher
Stanford University — Kundaje Lab
Visiting researcher working on sequence-based deep learning models of chromatin and gene regulation.
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2019 - 2019 San Diego, CA
Bioinformatics Intern
Ferring Pharmaceuticals
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2018 - 2019 Giessen, Germany
Professional Basketball Player
Giessen 46ers (Basketball Bundesliga, Germany)
Guard. Averaged 11.5 points, 5.4 rebounds, and 3.5 assists per game.
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2017 - 2018 Ontario, Canada
Professional Basketball Player
Niagara River Lions (NBL Canada)
First professional season in the National Basketball League of Canada.
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2019 - 2021 La Jolla, CA
Graduate Assistant Coach
UC San Diego Men's Basketball
Coached and mentored Division I/II student-athletes while pursuing my PhD.
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2022 - 2023 UC San Diego
Co-Founder
Deep Learning for Bioinformatics (DL4B)
Co-founded a student group on deep learning methods for bioinformatics.
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2021 - 2023 Chair of Student Wellness
Graduate Bioinformatics Council, UC San Diego
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2022 - 2023 Research Mentor
UC San Diego SURF & ENLACE Programs
Education
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2019 - 2025 La Jolla, CA
Ph.D., Bioinformatics & Systems Biology
University of California, San Diego
Carter Lab — advised by Hannah Carter
- GPA 4.0
- Dissertation on machine learning approaches for understanding non-coding regulatory variation
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2013 - 2017 La Jolla, CA
B.S., Bioengineering: Bioinformatics
University of California, San Diego
Revelle College
- GPA 4.0
- NCAA Division II student-athlete (men’s basketball)
Awards
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2025 Schmidt AI in Science Postdoctoral Fellowship
Eric & Wendy Schmidt / UC San Diego
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2021 NSF Graduate Research Fellowship — Honorable Mention
National Science Foundation
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2019 NIH T32 Training Grant (2019–2021)
National Institutes of Health
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2017 NCAA Postgraduate Scholarship
NCAA
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2017 Academic All-America of the Year
CoSIDA (College Sports Information Directors of America)
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2017 Player of the Year
California Collegiate Athletic Association (CCAA)
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2017 Amateur Star of the Year
San Diego Hall of Champions
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2017 Outstanding Graduate & Revelle College Outstanding Senior
UC San Diego
Publications
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2023 Predictive analyses of regulatory sequences with EUGENe
Nature Computational Science
Skills
Programming: Python, R, Bash, SQL
Machine Learning: PyTorch, Lightning, scikit-learn, Hugging Face
Genomics: ATAC-seq, RNA-seq, ChIP-seq, single-cell, Hi-C, GWAS
Tooling: Git, Docker, Snakemake, Nextflow, SLURM, GCP
Languages
English : Native
Interests
Research: regulatory genomics, machine learning for genomics, genetic medicine, the non-coding genome
Beyond work: basketball, guitar & songwriting, reading, coaching